Publications
RTG students and PIs in bold
Stauffer P, Kaspers MS, Swart AL, Ochtrop P, Siebels B, Pogenberg V, Ferreiro Otero D, Brockmeyer A, Schmid C, Janning P, Schlüter H, Hedberg C, Itzen A, Hilbi H. The Legionella phosphocholinase AnkX modulates IMPDH2 regulation and cytoophidia dynamics. bioRxiv. 2026 Jan 26:2026.01.26.701698. doi: 10.64898/2026.01.26.701698.
Uebler L, Pekarek N, Sandmann M, Berger J, Emmerich P, von Possel R, Pfefferle S, Fliegert R, Lütgehetmann M. Generation and Characterization of a Tagged Recombinant SARS-CoV-2 for Functional Replicase Studies. Preprints. 2025. doi: 10.20944/preprints202510.0092.v1.
Paraschiakos T, Yuan B, Hecht-Bucher M, Sopelniak K, Cervero P, Simon L, Zonjic K, Eggers D, Selle F, Li J, Biabani A, Linder S, Marlovits TC, Windhorst S. Evolutionarily conserved short linear motifs drive actin filament binding. Nat Cell Biol. 2026 Jul 6. doi: 10.1038/s41556-026-01979-9. Epub ahead of print. PMID: 42410114.
Kierspel T, de Santis E, Schamoni-Kast K, Blanchet C, Marklund EG, Caleman C, Uetrecht C. Native mass spectrometry meets X-rays for the elucidation of protein structures. Biochem Soc Trans. 2026 May 27;54(5):513-521. doi: 10.1042/BST20250111. PMID: 42101421; PMCID: PMC13161188.
Latham KA, Soh TK, Stanton RJ, Bosse JB, Goodbourn S, Strang BL. Human cytomegalovirus strain-specific differences in protein expression of type I IFN pathway proteins do not impact virus replication. Access Microbiol. 2026 Feb 19;8(2):001104.v3. doi: 10.1099/acmi.0.001104.v3. PMID: 41728058; PMCID: PMC12917765.
Sopelniak K, Batlouni R, Sun Q, Cervero P, Linder S. Phagocytic podosomes enable efficient uptake of Candida auris by primary human macrophages. Cell Rep. 2026 Mar 20;45(4):117167. doi: 10.1016/j.celrep.2026.117167. Epub ahead of print. PMID: 41863801.
Bekere I, Rob S, Lübbe J, Kulnik S, Berneking L, Huang J, Schnapp M, Diercks B-P, Guse AH, Carsten A, Ruckdeschel K, Aepfelbacher M. Immune activation of primary human macrophages is suppressed by the coordinated action of Yersinia effectors. mBio. 2026 Jan 14;17(1):e0254725. doi: 10.1128/mbio.02547-25. Epub 2025 Nov 24. PMID: 41277869; PMCID: PMC12802187.
Niedermüller K, Piwon N, Mesen-Ramirez JP, Zink L, Lemcke S, Liffner B, Fernandes CF, Farias GB, Alder A, Löw C, Dahan N, Wilson DW, Cubillán-Marín J, Gilberger TW. An atlas of novel microtubule-associated proteins in the malaria parasite Plasmodium falciparum. mBio. 2026 Jan 14;17(1):e0340725. doi: 10.1128/mbio.03407-25. Epub 2025 Dec 8. PMID: 41358875; PMCID: PMC12802302.
Knaack JIH#, List E#, Stalling D#, Sterrenberg VT, Meier C, Wagenknecht HA, Bosse JB. Live-Cell RNA Imaging via Clickable TriPPPro Nucleotide Reporters. Angew Chem Int Ed Engl. 2026 Jan 9;65(2):e16613. doi: 10.1002/anie.202516613. Epub 2025 Nov 27. PMID: 41310986; PMCID: PMC12790367.
Pazicky S, Tjia S, Farias GB, Piwon N, Philip N, Sobota RM, Waters AP, Gilberger TW, Bozdech Z. MAP-X reveals distinct protein complex dynamics across Plasmodium falciparum blood stages. Nat Microbiol. 2025 Dec;10(12):3229-3244. doi: 10.1038/s41564-025-02173-7. Epub 2025 Nov 28. PMID: 41315737.
Cubillán-Marín J, Fröhlke U, Ramón-Zamorano G, Mainye S, Mesén-Ramírez JP, Farias GB, Höhn J, Gilberger TW, Bártfai R and Spielmann T. Vesicle adaptors in malaria parasites show conservation and flexibility of protein sorting machinery. J Cell Biol. 2025 Dec 1;224(12):e202504062. doi: 10.1083/jcb.202504062. Epub 2025 Oct 13. PMID: 41082687.
Vollmer B, Ebel H, Rees R, Nentwig J, Mulvaney T, Schünemann J, Krull J, Topf M, Görlich D, Grünewald K. A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2. Nature. 2025 Oct;646(8084):433-441. doi: 10.1038/s41586-025-09438-5. Epub 2025 Sep 3. PMID: 40903574; PMCID: PMC12507662.
Bäumges H, Jelinek S, Lange H, Markmann S, Capriotti E, Häusser JA, Ilse MB, Braulke T, Lübke T. Deciphering α-L-Fucosidase Activity Contribution in Human and Mouse: Tissue α-L-Fucosidase FUCA1 Meets Plasma α-L-Fucosidase FUCA2. Cells. 2025 Aug 30;14(17):1355. doi: 10.3390/cells14171355. PMID: 40940767; PMCID: PMC12427801.
Runge S, Bilgen E, Magni A, Bonollo G, Colombo G, Itzen A, Lamb DC. The functional dynamics of FicD’s TPR domain are modulated by the interaction with ATP and BiP. Proc Natl Acad Sci U S A. 2025 Aug 26;122(34):e2500079122. doi: 10.1073/pnas.2500079122. Epub 2025 Aug 21. PMID: 40838883; PMCID: PMC12403077.
Dupré J, Dolata KM, Pei G, Molouki A, Goatley LC, Küchler R, Soh TK, Bosse JB, Fablet A, Le Dimna M, Karadjian G, Hirchaud E, Netherton CL, Dixon LK, Reis AL, Vitour D, Le Potier MF, Karger A, Caignard G. Exploring Virus-Host Interactions Through Combined Proteomic Approaches Identifies BANF1 as a New Essential Factor for African Swine Fever Virus. Mol Cell Proteomics. 2025 Jul 22;24(9):101038. doi: 10.1016/j.mcpro.2025.101038. Epub ahead of print. PMID: 40707000; PMCID: PMC12398270.
Mesén-Ramírez JP, Fuchs G, Burmester J, Farias GB, Alape-Flores AM, Singla S, Alder A, Cubillán-Marín J, Castro-Peña C, Lemcke S, Sondermann H, Prado M, Spielmann T, Wilson D, Gilberger TW. HOPS/CORVET tethering complexes are critical for endocytosis and protein trafficking to invasion related organelles in malaria parasites. PLoS Pathog. 2025 Apr 8;21(4):e1013053. doi: 10.1371/journal.ppat.1013053. PMID: 40198740; PMCID: PMC12011295.
Brauer BK, Chen Z, Beirow F, Li J, Meisinger D, Capriotti E, Schweizer M, Wagner L, Wienberg J, Hobohm L, Blume L, Qiao W, Narimatsu Y, Carette JE, Clausen H, Winter D, Braulke T, Jabs S, Voss M. GOLPH3 and GOLPH3L maintain Golgi localization of LYSET and a functional mannose 6-phosphate transport pathway. EMBO J. 2024 Nov 25. doi: 10.1038/s44318-024-00305-z. Epub ahead of print. PMID: 39587297.
Soh TK, Ognibene S, Sanders S, Schäper R, Kaufer BB, Bosse JB. A proteome-wide structural systems approach reveals insights into protein families of all human herpesviruses. Nat Commun. 2024 Nov 26;15(1):10230. doi: 10.1038/s41467-024-54668-2. PMID: 39592652; PMCID: PMC11599850.
*Pfefferle S, Schweizer M, Hartmann K, Berger J, Nörz D, Emmerich P, von Possel R, Giersch K, Pflüger LS, Bernreuther C, Glatzel M, Krasemann S, Brehm TT, Schulze Zur Wisch J, Fischer N, Schmiedel S, Aepfelbacher M, Lütgehetmann M. Severe mpox in an immunocompromised patient complicated by deep tissue infection: A case report. Heliyon. 2024 Oct 4;10(19):e38873. doi: 10.1016/j.heliyon.2024.e38873. PMID: 39444396; PMCID: PMC11497435.
Sabitzki R, Roßmann AL, Schmitt M, Flemming S, Guillén-Samander A, Behrens HM, Jonscher E, Höhn K, Fröhlke U, Spielmann T. Role of Rabenosyn-5 and Rab5b in host cell cytosol uptake reveals conservation of endosomal transport in malaria parasites. PLoS Biol. 2024 May 31;22(5):e3002639. doi: 10.1371/journal.pbio.3002639. PMID: 38820535.
Soh TK, Pfefferle S, Wurr S, von Possel R, Oestereich L, Rieger T, Uetrecht C, Rosenthal M, Bosse JB. A validated protocol to UV-inactivate SARS-CoV-2 and herpesvirus-infected cells. PLoS One. 2023 May 10;18(5):e0274065. doi: 10.1371/journal.pone.0274065. PMID: 37163509; PMCID: PMC10171616.
* Stanelle-Bertram S, Beck S, Mounogou NK, Schaumburg B, Stoll F, Al Jawazneh A, Schmal Z, Bai T, Zickler M, Beythien G, Becker K, de la Roi M, Heinrich F, Schulz C, Sauter M, Krasemann S, Lange P, Heinemann A, van Riel D, Leijten L, Bauer L, van den Bosch TPP, Lopuhaä B, Busche T, Wibberg D, Schaudien D, Goldmann T, Lüttjohann A, Ruschinski J, Jania H, Müller Z, Pinho Dos Reis V, Krupp-Buzimkic V, Wolff M, Fallerini C, Baldassarri M, Furini S, Norwood K, Käufer C, Schützenmeister N, von Köckritz-Blickwede M, Schroeder M, Jarczak D, Nierhaus A, Welte T, Kluge S, McHardy AC, Sommer F, Kalinowski J, Krauss-Etschmann S, Richter F, von der Thüsen J, Baumgärtner W, Klingel K, Ondruschka B; GEN-COVID Multicenter Study Group; Renieri A, Gabriel G. CYP19A1 mediates severe SARS-CoV-2 disease outcome in males. Cell Rep Med. 2023 Sep 19;4(9):101152. doi: 10.1016/j.xcrm.2023.101152. Epub 2023 Aug 12. PMID: 37572667; PMCID: PMC10518605.
* Sterrenberg VT#, Stalling D#, Knaack JIH, Soh TK, Bosse JB, Meier C. A TriPPPro-Nucleotide Reporter with Optimized Cell-Permeable Dyes for Metabolic Labeling of Cellular and Viral DNA in Living Cells. Angew Chem Int Ed Engl. 2023 Sep 18;62(38):e202308271. doi: 10.1002/anie.202308271. Epub 2023 Aug 9. PMID: 37435767.
* Kaspers MS, Pogenberg V, Pett C, Ernst S, Ecker F, Ochtrop P, Groll M, Hedberg C, Itzen A. Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b. Nat Commun. 2023 Apr 19;14(1):2245. doi: 10.1038/s41467-023-37621-7. PMID: 37076474; PMCID: PMC10115812.